Non-invasive (19)F MR spectroscopy of 5-fluorocytosine to 5-fluorouracil conversion by recombinant Salmonella in tumours

The aim of this study was to evaluate the applicability of fluorine-19 magnetic resonance spectroscopy ((19)F MRS) for monitoring in vivo the conversion of 5-fluorocytosine (5-FC) to 5-fluorouracil (5-FU) after using an attenuated Salmonella Typhimurium strain recombinant to provide cytosine deamina...

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Hlavní autoři: Dresselaers, T, Theys, J, Nuyts, S, Wouters, B, de Bruijn, E, Anné, J, Lambin, P, Van Hecke, P, Landuyt, W
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2003
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394413/
https://ncbi.nlm.nih.gov/pubmed/14583786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601345
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