The potential for oral combination chemotherapy of 5′-deoxy-5-fluorouridine, a 5-FU prodrug, and cyclophosphamide for metastatic breast cancer

Preclinical studies have demonstrated the synergistic anti-tumour activity of combination therapy with the oral cytostatics, 5′-deoxy-5-fluorouridine (5′-DFUR) and cyclophosphamide (CPA), in human breast cancer xenograft models. This study was performed to evaluate the efficacy and safety of this or...

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Detalhes bibliográficos
Main Authors: Yoshimoto, M, Tada, K, Tokudome, N, Kutomi, G, Tanabe, M, Goto, T, Nishimura, S, Makita, M, Kasumi, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Clinical
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394400/
https://ncbi.nlm.nih.gov/pubmed/14583760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601350
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