Potentiation of radiation therapy by the oncolytic adenovirus dl1520 (ONYX-015) in human malignant glioma xenografts

In spite of aggressive surgery, irradiation and/or chemotherapy, treatment of malignant gliomas remains a major challenge in adults and children due to high treatment failure. We have demonstrated significant cell lysis and antitumour activity of the E1B-55 kDa-gene-deleted adenovirus ONYX-015 (dl15...

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Detalhes bibliográficos
Main Authors: Geoerger, B, Grill, J, Opolon, P, Morizet, J, Aubert, G, Lecluse, Y, van Beusechem, V W, Gerritsen, W R, Kirn, D H, Vassal, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394372/
https://ncbi.nlm.nih.gov/pubmed/12888833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601102
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