Bcl-x(L) antisense oligonucleotides radiosensitise colon cancer cells

Advanced colon cancer is a malignancy with poor response to various treatment modalities including ionising radiation (IR) and chemotherapy. Both IR and chemotherapeutic agents have been shown to act by inducing apoptosis, a type of cell death antagonised by the Bcl-x(L) gene product. Since approxim...

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Main Authors: Wacheck, V, Selzer, E, Günsberg, P, Lucas, T, Meyer, H, Thallinger, C, Monia, B P, Jansen, B
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2003
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394316/
https://ncbi.nlm.nih.gov/pubmed/14520471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601254
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