In vitro selectivity, in vivo biodistribution and tumour uptake of annexin V radiolabelled with a positron emitting radioisotope

The availability of a noninvasive method to detect and quantify apoptosis in tumours will enable tumour response to several cancer therapies to be assessed. We have synthesised two radiotracers, annexin V and the N-succinimidyl-3-iodobenzoic acid (SIB) derivative of annexin V, labelled with radio-io...

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Detalhes bibliográficos
Main Authors: Collingridge, D R, Glaser, M, Osman, S, Barthel, H, Hutchinson, O C, Luthra, S K, Brady, F, Bouchier-Hayes, L, Martin, S J, Workman, P, Price, P, Aboagye, E O
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394302/
https://ncbi.nlm.nih.gov/pubmed/14520468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601262
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