Homeostatic expansion and phenotypic conversion of naïve T cells in response to self peptide/MHC ligands

Recent data suggest that survival of resting, naïve T cells requires an interaction with self MHC molecules. From analysis of the class I MHC-restricted T cell receptor transgenic strain OT-I, we report a different response. Rather than merely surviving, these T cells proliferated slowly after trans...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Kieper, William C., Jameson, Stephen C.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1999
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23943/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10557316/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.23.13306
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