Inhibition of growth and induction of apoptosis in human breast cancer by transfection of gef gene

The gef gene has cell-killing functions in Escherichia coli. To evaluate the feasibility of using this gene as a new strategy for cancer therapy, we transfected it in MCF-7 cells derived from breast cancer (MCF-7TG). The gef gene was cloned in a pMAMneo vector under the control of a mouse mammary tu...

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Detalhes bibliográficos
Main Authors: Boulaiz, H, Prados, J, Melguizo, C, García, Á M, Marchal, J A, Ramos, J L, Carrillo, E, Vélez, C, Aranega, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394231/
https://ncbi.nlm.nih.gov/pubmed/12838323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601064
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