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Reducing the Genotoxic Potential of Retroviral Vectors
The recent development of leukemia in gene therapy patients with X-linked severe combined immunodeficiency disease due to retroviral vector insertional mutagenesis has prompted reassessment of the genotoxic potential of integrating vector systems. In this chapter, various strategies are described to...
שמור ב:
| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394199/ https://ncbi.nlm.nih.gov/pubmed/18470646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-248-3_12 |
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