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Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome

Fragile X syndrome (FXS) has so far resisted efforts to define the basic cellular defects caused by the absence of a single protein, fragile X mental retardation protein (FMRP), because the patients have a wide variety of symptoms of varying severity. Immature-appearing dendritic spines on neurons f...

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Detalhes bibliográficos
Main Authors: Kim, Soong Ho, Markham, Julie A., Weiler, Ivan Jeanne, Greenough, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393788/
https://ncbi.nlm.nih.gov/pubmed/18332424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800257105
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