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Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus

The JFH1 strain of hepatitis C virus (HCV) is unique among HCV isolates, in that the wild-type virus can traverse the entire replication cycle in cultured cells. However, without adaptive mutations, only low levels of infectious virus are produced. In the present study, the effects of five mutations...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Russell, Rodney S., Meunier, Jean-Christophe, Takikawa, Shingo, Faulk, Kristina, Engle, Ronald E., Bukh, Jens, Purcell, Robert H., Emerson, Suzanne U.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393785/
https://ncbi.nlm.nih.gov/pubmed/18334634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800422105
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