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Oncogenic stimulation recruits cyclin-dependent kinase in the cell cycle start in rat fibroblast

The rat fibroblast NRK cells are transformed reversibly by a combination of growth factors. When stimulated with serum, NRK cells rely on cyclin-dependent kinase 4 (Cdk4) for their S phase entry. However, when stimulated with serum containing oncogenic growth factors, they come to rely on either Cdk...

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Main Authors: Jinno, Shigeki, Hung, Shih-Chieh, Yamamoto, Hanako, Lin, Jie, Nagata, Akihisa, Okayama, Hiroto
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC23924/
https://ncbi.nlm.nih.gov/pubmed/10557297
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