Monitoring the assembly of Ig light-chain amyloid fibrils by atomic force microscopy

Aggregation of Ig light chains to form amyloid fibrils is a characteristic feature of light-chain amyloidosis, a light-chain deposition disease. A recombinant variable domain of the light chain SMA was used to form amyloid fibrils in vitro. Fibril formation was monitored by atomic force microscopy i...

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Detalhes bibliográficos
Main Authors: Ionescu-Zanetti, Cristian, Khurana, Ritu, Gillespie, Joel R., Petrick, Jay S., Trabachino, Lynne C., Minert, Lauren J., Carter, Sue A., Fink, Anthony L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23920/
https://ncbi.nlm.nih.gov/pubmed/10557293
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