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Rapid culling of the CD4 repertoire in the transition from effector to memory

Requirements for CD4 memory differentiation were analyzed using adoptively transferred SMARTA TCR transgenic cells specific for an LCMV epitope. Following LCMV infection, effector and memory differentiation of SMARTA cells mimicked the endogenous CD4 response. In contrast, infection with a recombina...

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Main Authors: Williams, Matthew A., Ravkov, Eugene V., Bevan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391296/
https://ncbi.nlm.nih.gov/pubmed/18356084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.02.014
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