Intra-arrest cooling with delayed reperfusion yields higher survival than earlier normothermic resuscitation in a mouse model of cardiac arrest

BACKGROUND: Therapeutic hypothermia (TH) represents an important method to attenuate post-resuscitation injury after cardiac arrest. Laboratory investigations have suggested that induction of hypothermia before return of spontaneous circulation (ROSC) may confer the greatest benefit. We hypothesized...

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Main Authors: Zhao, Danhong, Abella, Benjamin S., Beiser, David G., Alvarado, Jason P., Wang, Huashan, Hamann, Kimm J., Vanden Hoek, Terry L., Becker, Lance B.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391241/
https://ncbi.nlm.nih.gov/pubmed/18096292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resuscitation.2007.10.015
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