Vascular tube formation on matrix metalloproteinase-1-damaged collagen

Connective tissue damage and angiogenesis are both important features of tumour growth and invasion. Here, we show that endothelial cells maintained on a three-dimensional lattice of intact polymerised collagen formed a monolayer of cells with a cobblestone morphology. When the collagen was exposed...

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Autori principali: Varani, J, Perone, P, Warner, R L, Dame, M K, Kang, S, Fisher, G J, Voorhees, J J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
Soggetti:
Molecular Diagnostics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391116/
https://ncbi.nlm.nih.gov/pubmed/18443597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604357
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