The protective role of transferrin in Müller glial cells after iron-induced toxicity

PURPOSE: Transferrin (Tf) expression is enhanced by aging and inflammation in humans. We investigated the role of transferrin in glial protection. METHODS: We generated transgenic mice (Tg) carrying the complete human transferrin gene on a C57Bl/6J genetic background. We studied human (hTf) and mous...

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Bibliographic Details
Main Authors: Picard, Emilie, Fontaine, Isabelle, Jonet, Laurent, Guillou, Florian, Behar-Cohen, Francine, Courtois, Yves, Jeanny, Jean-Claude
Format: Artigo
Language:Inglês
Published: Molecular Vision 2008
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391081/
https://ncbi.nlm.nih.gov/pubmed/18509548
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