Overexpressed or intraperitoneally injected human transferrin prevents photoreceptor degeneration in rd10 mice

PURPOSE: Retinal degeneration has been associated with iron accumulation in age-related macular degeneration (AMD), and in several rodent models that had one or several iron regulating protein impairments. We investigated the iron concentration and the protective role of human transferrin (hTf) in r...

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Bibliographic Details
Main Authors: Picard, Emilie, Jonet, Laurent, Sergeant, Claire, Vesvres, Marie-Hélène, Behar-Cohen, Francine, Courtois, Yves, Jeanny, Jean-Claude
Format: Artigo
Language:Inglês
Published: Molecular Vision 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002967/
https://ncbi.nlm.nih.gov/pubmed/21179240
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