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Sirolimus Reduces Polycystic Liver Volume in ADPKD Patients
The immunosuppressive agent sirolimus exerts an antiproliferative effect by inhibiting mammalian target of rapamycin (mTOR). Because excessive proliferation of the biliary epithelium is a prominent feature of the polycystic liver that accompanies autosomal dominant polycystic kidney disease (ADPKD),...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2391057/ https://ncbi.nlm.nih.gov/pubmed/18199797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007050626 |
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