Fibrocystin/Polyductin Modulates Renal Tubular Formation by Regulating Polycystin-2 Expression and Function

Autosomal recessive polycystic kidney disease is caused by mutations in PKHD1, which encodes the membrane-associated receptor-like protein fibrocystin/polyductin (FPC). FPC associates with the primary cilia of epithelial cells and co-localizes with the Pkd2 gene product polycystin-2 (PC2), suggestin...

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Главные авторы: Kim, Ingyu, Fu, Yulong, Hui, Kwokyin, Moeckel, Gilbert, Mai, Weiyi, Li, Cunxi, Liang, Dan, Zhao, Ping, Ma, Jie, Chen, Xing-Zhen, George, Alfred L., Coffey, Robert J., Feng, Zhong-Ping, Wu, Guanqing
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2008
Предметы:
Basic Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391052/
https://ncbi.nlm.nih.gov/pubmed/18235088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007070770
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