Loss of Polycystin-1 Inhibits Bicc1 Expression during Mouse Development

Bicc1 is a mouse homologue of Drosophila Bicaudal-C (dBic-C), which encodes an RNA-binding protein. Orthologs of dBic-C have been identified in many species, from C. elegans to humans. Bicc1-mutant mice exhibit a cystic phenotype in the kidney that is very similar to human polycystic kidney disease....

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Detalhes bibliográficos
Main Authors: Lian, Peiwen, Li, Ao, Li, Yuan, Liu, Haichao, Liang, Dan, Hu, Bo, Lin, De, Jiang, Tang, Moeckel, Gilbert, Qin, Dahui, Wu, Guanqing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940423/
https://ncbi.nlm.nih.gov/pubmed/24594709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088816
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