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ABNORMAL MOTOR FUNCTION AND DOPAMINE NEUROTRANSMISSION IN DYT1 ΔGAG TRANSGENIC MICE

A single GAG deletion in Exon 5 of the TOR1A gene is associated with a form of early-onset primary dystonia showing less than 40% penetrance. To provide a framework for cellular and systems study of DYT1 dystonia, we characterized the genetic, behavioral, morphological and neurochemical features of...

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Detalhes bibliográficos
Main Authors: Zhao, Yu, DeCuypere, Michael, LeDoux, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390904/
https://ncbi.nlm.nih.gov/pubmed/18299128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2007.12.027
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