Tolerance to 3,4-Methylenedioxymethamphetamine (MDMA) in Rats Exposed to Single High-Dose Binges

3,4-Methylenedioxymethamphetamine (MDMA or Ecstasy) stimulates the transporter-mediated release of monoamines, including serotonin (5-HT). High-dose exposure to MDMA causes persistent 5-HT deficits (e.g., depletion of brain 5-HT) in animals, yet the functional and clinical relevance of such deficits...

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Main Authors: Baumann, Michael H., Clark, Robert D., Franken, Frederick H., Rutter, John J., Rothman, Richard B.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390896/
https://ncbi.nlm.nih.gov/pubmed/18313226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.01.007
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