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TGFβ1 and TNFα potentiate nitric oxide production in astrocyte cultures by recruiting distinct sub-populations of cells to express NOS-2
Nitric oxide (NO) synthase-2 (NOS-2), a key source of NO at sites of neuroinflammation, is induced in astrocyte cultures treated with lipopolysaccharide (LPS) plus interferon-γ (IFNγ). A recent study examining the regulation of astrocytic NOS-2 expression demonstrated that transforming growth factor...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2390826/ https://ncbi.nlm.nih.gov/pubmed/18035449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2007.10.010 |
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