TGFβ1 and TNFα potentiate nitric oxide production in astrocyte cultures by recruiting distinct sub-populations of cells to express NOS-2

Nitric oxide (NO) synthase-2 (NOS-2), a key source of NO at sites of neuroinflammation, is induced in astrocyte cultures treated with lipopolysaccharide (LPS) plus interferon-γ (IFNγ). A recent study examining the regulation of astrocytic NOS-2 expression demonstrated that transforming growth factor...

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Hlavní autoři: Hamby, Mary E., Gragnolati, Ariel R., Hewett, Sandra J., Hewett, James A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390826/
https://ncbi.nlm.nih.gov/pubmed/18035449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2007.10.010
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