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The PIWI proteins SMEDWI-2 and SMEDWI-3 are required for stem cell function and piRNA expression in planarians

PIWI proteins are expressed in germ cells in a wide variety of metazoans, where they participate in the synthesis and function of a novel class of small RNAs called PIWI associated RNAs (piRNAs). One function of piRNAs is to preserve the integrity of the germline genome by silencing transposons, tho...

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Bibliographic Details
Main Authors: Palakodeti, Dasaradhi, Smielewska, Magda, Lu, Yi-Chien, Yeo, Gene W., Graveley, Brenton R.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390803/
https://ncbi.nlm.nih.gov/pubmed/18456843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1085008
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