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Multiple Host Barriers Restrict Poliovirus Trafficking in Mice

RNA viruses such as poliovirus have high mutation rates, and a diverse viral population is likely required for full virulence. We previously identified limitations on poliovirus spread after peripheral injection of mice expressing the human poliovirus receptor (PVR), and we hypothesized that the hos...

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Detalhes bibliográficos
Main Authors: Kuss, Sharon K., Etheredge, Chris A., Pfeiffer, Julie K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390757/
https://ncbi.nlm.nih.gov/pubmed/18535656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000082
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