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Multiple Host Barriers Restrict Poliovirus Trafficking in Mice

RNA viruses such as poliovirus have high mutation rates, and a diverse viral population is likely required for full virulence. We previously identified limitations on poliovirus spread after peripheral injection of mice expressing the human poliovirus receptor (PVR), and we hypothesized that the hos...

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書目詳細資料
Main Authors: Kuss, Sharon K., Etheredge, Chris A., Pfeiffer, Julie K.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390757/
https://ncbi.nlm.nih.gov/pubmed/18535656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000082
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