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A Thermodynamic Switch for Chromosome Colocalization
A general model for the early recognition and colocalization of homologous DNA sequences is proposed. We show, on thermodynamic grounds, how the distance between two homologous DNA sequences is spontaneously regulated by the concentration and affinity of diffusible mediators binding them, which act...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Genetics Society of America
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2390650/ https://ncbi.nlm.nih.gov/pubmed/18493085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.083154 |
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