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High Rates of “Unselected” Aneuploidy and Chromosome Rearrangements in tel1 mec1 Haploid Yeast Strains
The yeast TEL1 and MEC1 genes (homologous to the mammalian ATM and ATR genes, respectively) serve partially redundant roles in the detection of DNA damage and in the regulation of telomere length. Haploid yeast tel1 mec1 strains were subcultured nonselectively for ∼200 cell divisions. The subculture...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Genetics Society of America
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2390603/ https://ncbi.nlm.nih.gov/pubmed/18458104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.086603 |
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