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Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis

BACKGROUND: A common element among cancer cells is the presence of improperly controlled transcription. In these cells, the degree of specific activation of some genes is abnormal, and altering the aberrant transcription may therefore directly target cancer. TFIIS is a transcription elongation facto...

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Detalhes bibliográficos
Main Authors: Hubbard, Kyle, Catalano, Jennifer, Puri, Raj K, Gnatt, Averell
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390572/
https://ncbi.nlm.nih.gov/pubmed/18474089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-133
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