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Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis

BACKGROUND: A common element among cancer cells is the presence of improperly controlled transcription. In these cells, the degree of specific activation of some genes is abnormal, and altering the aberrant transcription may therefore directly target cancer. TFIIS is a transcription elongation facto...

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Autors principals: Hubbard, Kyle, Catalano, Jennifer, Puri, Raj K, Gnatt, Averell
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390572/
https://ncbi.nlm.nih.gov/pubmed/18474089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-133
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