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14-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 Vpr

BACKGROUND: Despite continuing advances in our understanding of AIDS pathogenesis, the mechanism of CD4+ T cell depletion in HIV-1-infected individuals remains unclear. The HIV-1 Vpr accessory protein causes cell death, likely through a mechanism related to its ability to arrest cells in the G(2),M...

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Detalhes bibliográficos
Main Authors: Bolton, Diane L, Barnitz, Robert A, Sakai, Keiko, Lenardo, Michael J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390528/
https://ncbi.nlm.nih.gov/pubmed/18445273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-3-17
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