Glycosylation differences between the normal and pathogenic prion protein isoforms

Prion protein consists of an ensemble of glycosylated variants or glycoforms. The enzymes that direct oligosaccharide processing, and hence control the glycan profile for any given glycoprotein, are often exquisitely sensitive to other events taking place within the cell in which the glycoprotein is...

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Main Authors: Rudd, Pauline M., Endo, Tama, Colominas, Cristina, Groth, Darlene, Wheeler, Susan F., Harvey, David J., Wormald, Mark R., Serban, Hana, Prusiner, Stanley B., Kobata, Akira, Dwek, Raymond A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 1999
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC23897/
https://ncbi.nlm.nih.gov/pubmed/10557270
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