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A FAK/Src Chimera With Gain-of-Function Properties Promotes Formation of Large Peripheral Adhesions Associated With Dynamic Actin Assembly
Formation of a complex between the tyrosine kinases FAK and Src is a key integrin-mediated signaling event implicated in cell motility, survival, and proliferation. Past studies indicate that FAK functions in the complex primarily as a “scaffold,” acting to recruit and activate Src within cell/matri...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2387247/ https://ncbi.nlm.nih.gov/pubmed/17922492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.20241 |
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