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The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB
Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is an autosomal dominant dementia that is characterized by the retention of polymers of neuroserpin as inclusions within the endoplasmic reticulum (ER) of neurons. We have developed monoclonal antibodies that detect polymerized neuros...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2387220/ https://ncbi.nlm.nih.gov/pubmed/18267959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn041 |
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