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Prostasin expression is regulated by airway surface liquid volume and is increased in cystic fibrosis

Airway surface liquid (ASL) absorption is initiated by Na(+) entry via epithelial Na(+) channels (ENaC), which establishes an osmotic gradient that drives fluid from the luminal to serosal airway surface. We and others have recently reported that a protease/anti-protease balance regulates ENaC in hu...

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Hlavní autoři: Myerburg, Mike M., McKenna, Erin E., Luke, Cliff J., Frizzell, Raymond A., Kleyman, Thomas R., Pilewski, Joseph M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2387194/
https://ncbi.nlm.nih.gov/pubmed/18310226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00437.2007
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