Neuregulin-1 Type III Determines the Ensheathment Fate of Axons

The signals that determine whether axons are ensheathed or myelinated by Schwann cells have long been elusive. We now report that threshold levels of neuregulin-1 (NRG1) type III on axons determine their ensheathment fate. Ensheathed axons express low levels whereas myelinated fibers express high le...

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Detalhes bibliográficos
Main Authors: Taveggia, Carla, Zanazzi, George, Petrylak, Ashley, Yano, Hiroko, Rosenbluth, Jack, Einheber, Steven, Xu, Xiaorong, Esper, Raymond M., Loeb, Jeffrey A., Shrager, Peter, Chao, Moses V., Falls, Douglas L., Role, Lorna, Salzer, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2387056/
https://ncbi.nlm.nih.gov/pubmed/16129398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2005.08.017
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