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Lack of Response to Exogenous Interferon-α in the Liver of HCV Chronically Infected Chimpanzees

The mechanism of the interferon-alpha (IFNα)-induced antiviral response is not completely understood. We recently examined the transcriptional response to IFNα in uninfected chimpanzees. The transcriptional response to IFNα in the liver and peripheral blood mononuclear cells (PBMC) was rapidly induc...

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Autori principali: Lanford, Robert E., Guerra, Bernadette, Bigger, Catherine B., Lee, Helen, Chavez, Deborah, Brasky, Kathleen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386986/
https://ncbi.nlm.nih.gov/pubmed/17668868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.21776
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