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Lack of Response to Exogenous Interferon-α in the Liver of HCV Chronically Infected Chimpanzees

The mechanism of the interferon-alpha (IFNα)-induced antiviral response is not completely understood. We recently examined the transcriptional response to IFNα in uninfected chimpanzees. The transcriptional response to IFNα in the liver and peripheral blood mononuclear cells (PBMC) was rapidly induc...

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Autors principals: Lanford, Robert E., Guerra, Bernadette, Bigger, Catherine B., Lee, Helen, Chavez, Deborah, Brasky, Kathleen M.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386986/
https://ncbi.nlm.nih.gov/pubmed/17668868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.21776
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