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Biodisposition and metabolism of [(18)F]fluorocholine in 9L glioma cells and 9L glioma-bearing Fisher rats

PURPOSE: [(18)F]Fluorocholine [(18)F]FCH) was developed as an analog of [(11)C]choline for tumor imaging, however, its metabolic handling remains ill-defined. In this study, the metabolism of [(18)F]FCH is evaluated in cultured 9L glioma cells and Fisher 344 rats bearing 9L glioma tumors. METHODS: 9...

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Detalhes bibliográficos
Main Authors: Bansal, Aditya, Shuyan, Wang, Hara, Toshiko, Harris, Robert A., DeGrado, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386980/
https://ncbi.nlm.nih.gov/pubmed/18264706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-008-0736-y
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