Effective Detection of Human Leukocyte Antigen Risk Alleles in Celiac Disease Using Tag Single Nucleotide Polymorphisms

BACKGROUND: The HLA genes, located in the MHC region on chromosome 6p21.3, play an important role in many autoimmune disorders, such as celiac disease (CD), type 1 diabetes (T1D), rheumatoid arthritis, multiple sclerosis, psoriasis and others. Known HLA variants that confer risk to CD, for example,...

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Main Authors: Monsuur, Alienke J., de Bakker, Paul I. W., Zhernakova, Alexandra, Pinto, Dalila, Verduijn, Willem, Romanos, Jihane, Auricchio, Renata, Lopez, Ana, van Heel, David A., Crusius, J. Bart A, Wijmenga, Cisca
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386975/
https://ncbi.nlm.nih.gov/pubmed/18509540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002270
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