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MMP19 Is Essential for T Cell Development and T Cell-Mediated Cutaneous Immune Responses

Matrix metalloproteinase-19 (MMP19) affects cell proliferation, adhesion, and migration in vitro but its physiological role in vivo is poorly understood. To determine the function of MMP19, we generated mice deficient for MMP19 by disrupting the catalytic domain of mmp19 gene. Although MMP19-deficie...

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Bibliografiske detaljer
Main Authors: Beck, Inken M., Rückert, René, Brandt, Katja, Mueller, Markus S., Sadowski, Thorsten, Brauer, Rena, Schirmacher, Peter, Mentlein, Rolf, Sedlacek, Radislav
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386969/
https://ncbi.nlm.nih.gov/pubmed/18523579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002343
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