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The PIP2 binding mode of the C2 domains of rabphilin-3A

Phosphatidylinositol-4,5-bisphosphate (PIP2) is a key player in the neurotransmitter release process. Rabphilin-3A is a neuronal C2 domain tandem containing protein that is involved in this process. Both its C2 domains (C2A and C2B) are able to bind PIP2. The investigation of the interactions of the...

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Bibliographic Details
Main Authors: Montaville, Pierre, Coudevylle, Nicolas, Radhakrishnan, Anand, Leonov, Andrei, Zweckstetter, Markus, Becker, Stefan
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386734/
https://ncbi.nlm.nih.gov/pubmed/18434502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073326608
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