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Diverse metabolic model parameters generate similar methionine cycle dynamics
Parameter estimation constitutes a major challenge in dynamic modeling of metabolic networks. Here we examine, via computational simulations, the influence of system nonlinearity and the nature of available data on the distribution and predictive capability of identified model parameters. Simulated...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2386584/ https://ncbi.nlm.nih.gov/pubmed/18313076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2007.12.009 |
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