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Likelihood-Based Association Analysis for Nuclear Families and Unrelated Subjects with Missing Genotype Data
Missing data occur in genetic association studies for several reasons including missing family members and uncertain haplotype phase. Maximum likelihood is a commonly used approach to accommodate missing data, but it can be difficult to apply to family-based association studies, because of possible...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2386559/ https://ncbi.nlm.nih.gov/pubmed/18382088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000119108 |
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