Tumorigenicity of IL-1α- and IL-1β-Deficient Fibrosarcoma Cells

Analyzing the growth of fibrosarcoma lines derived from IL-1α-, IL-1β- , or IL-1αβ-knockout ((-/-)) mice in the immunocompetent host revealed that tumor-derived IL-1α and IL-1β exert strong and opposing effects on immune response induction, which prohibited the evaluation of a potential impact on tu...

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Hauptverfasser: Nazarenko, Irina, Marhaba, Rachid, Reich, Eli, Voronov, Elena, Vitacolonna, Mario, Hildebrand, Dagmar, Elter, Elena, Rajasagi, Mohini, Apte, Ron N, Zöller, Margot
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386540/
https://ncbi.nlm.nih.gov/pubmed/18516292
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