Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury

Mortality from sepsis has remained high despite recent advances in supportive and targeted therapies. Toll-like receptors (TLRs) sense bacterial products and stimulate pathogenic innate immune responses. Mice deficient in the common adapter protein MyD88, downstream from most TLRs, have reduced mort...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yasuda, Hideo, Leelahavanichkul, Asada, Tsunoda, Shinichiro, Dear, James W., Takahashi, Yoshiyuki, Ito, Shuichi, Hu, Xuzhen, Zhou, Hua, Doi, Kent, Childs, Richard, Klinman, Dennis M., Yuen, Peter S.T., Star, Robert A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386262/
https://ncbi.nlm.nih.gov/pubmed/18305095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00461.2007
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