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Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2–dependent RNA granules

Central nervous system myelination requires the synthesis of large amounts of myelin basic protein (MBP) at the axon–glia contact site. MBP messenger RNA (mRNA) is transported in RNA granules to oligodendroglial processes in a translationally silenced state. This process is regulated by the trans-ac...

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Autors principals: White, Robin, Gonsior, Constantin, Krämer-Albers, Eva-Maria, Stöhr, Nadine, Hüttelmaier, Stefan, Trotter, Jacqueline
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386098/
https://ncbi.nlm.nih.gov/pubmed/18490510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706164
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