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Proteasome regulation of activation-induced T cell death

Lactacystin, a microbial metabolite that inhibits protease activity only in the proteasome, was used to study the role of the proteasome in the activation-induced cell death (AICD) of T cells. Lactacystin induces DNA fragmentation and apoptosis in a T cell hybridoma (DO.11.10) in a dose-dependent ma...

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Detalhes bibliográficos
Main Authors: Cui, Haili, Matsui, Ken, Omura, Satoshi, Schauer, Stephanie L., Matulka, Ray A., Sonenshein, Gail E., Ju, Shyr-Te
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23853/
https://ncbi.nlm.nih.gov/pubmed/9207123
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