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Attenuated Salmonella typhimurium with IL-2 Gene Reduces Pulmonary Metastases in Murine Osteosarcoma

Historically, osteosarcoma has been a problematic metastatic disease, with 40–80% of patients developing pulmonary metastasis after primary tumor resection. Recent treatment advancements have reduced the occurrence of metastatic lesions to less than 30%. Using attenuated Salmonella typhimurium, we p...

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Autors principals: Sorenson, Brent S., Banton, Kaysie L., Frykman, Natalie L., Leonard, Arnold S., Saltzman, Daniel A.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384016/
https://ncbi.nlm.nih.gov/pubmed/18421536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-008-0243-2
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