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Direct isolation of human BRCA2 gene by transformation-associated recombination in yeast

Mutant forms of the BRCA2 gene contribute significantly to hereditary breast cancer. Isolation of the normal and mutant forms of the BRCA2 gene with its natural promoter would greatly facilitate analysis of the gene and its contribution to breast cancer. We have accomplished the direct isolation of...

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Autori principali: Larionov, Vladimir, Kouprina, Natalya, Solomon, Gregory, Barrett, J. Carl, Resnick, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC23830/
https://ncbi.nlm.nih.gov/pubmed/9207100
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