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Segments missing from the draft human genome sequence can be isolated by transformation-associated recombination cloning in yeast

The reported draft human genome sequence includes many contigs that are separated by gaps of unknown sequence. These gaps may be due to chromosomal regions that are not present in the Escherichia coli libraries used for DNA sequencing because they cannot be cloned efficiently, if at all, in bacteria...

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書誌詳細
主要な著者: Kouprina, Natalay, Leem, Sun-Hee, Solomon, Greg, Ly, Albert, Koriabine, Maxim, Otstot, John, Pak, Eugene, Dutra, Amalia, Zhao, Shaying, Barrett, J. Carl, Larionov, Vladimir
フォーマット: Artigo
言語:Inglês
出版事項: 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315894/
https://ncbi.nlm.nih.gov/pubmed/12634842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor766
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